Garcinia cambogia, a tropical fruit also known as the Malabar tamarind, is a popular weight-loss supplement. People say it blocks your body’s ability to make fat and it puts the brakes on your appetite. Loss of excess weight could help could help keep blood sugar and cholesterol levels in check, too.

The active ingredient in the fruit’s rind, hydroxycitric acid, or HCA, appears to block an enzyme called citrate lyase, which your body uses to make fat. It also raises levels of the brain chemical serotonin, which may make you feel less hungry.